手机版 | 设首页 | 加收藏
当前位置: 网站首页 > 热点资讯 > 研究热点 > 文章

The immunosuppressive effect of embryonic stem cel

来源:    作者:    时间:2011-03-22    点击: 次   

Recently, both embryonic stetn cells and mesenchymal stem cells have been demonstrated to have immunosuppressive effects. The purpose of this study was to elucidate whether the embryonic stem cells and/or mesenchymal stem cells modulate both primary and secondary alloimmune responses. Both stem cells suppressed in vftro proliferation and cytokine production in primary alloimmune responses. They also suppressed in vitro proliferation and cytokine production of the allosensicized CD44 * memory T cells. However, they failed to prolong skin graft survival across both A major mismatch barrier (BALB/C. C57BL6/J) and a minor mismatch barrier (male to female). In conclusion, both embryonic slem cells and mcsenchymal stem cells can suppress secondary alloimmune response in vitro as welt as primary alloimniune responses; however, neither embryonic stem cells nor mesenchymal stem cells suppressed ailograft rejection in stringent murine skin transplantation models.

上一篇:Cell Stem Cell:Another Horse in the Meta-Stable St

下一篇:Brain tumor stem cells

  • 同济大学高绍荣/王译萱团队揭示人多能干细胞命运转变中的谱系特征
    同济大学高绍荣/王译萱团队揭示人多能干细..
  • 同济大学李维达团队及合作者首次通过基因编辑实现更成熟和更稳定的人多能干细胞到胰岛细胞的诱导分化技术
    同济大学李维达团队及合作者首次通过基因编..
  • 中国生物新冠灭活疫苗上市 国家卫健委全民免费提供
    中国生物新冠灭活疫苗上市 国家卫健委全民..
  • 2020诺贝尔化学奖 CRISPR Cas9技术获奖 张锋失之交臂
    2020诺贝尔化学奖 CRISPR Cas9技术..
  • 2020年诺贝尔生理学/医学奖揭晓 丙肝病毒研究获奖
    2020年诺贝尔生理学/医学奖揭晓 丙肝病毒研..
  • 1
  • 2
  • 3
  • 4
  • 5
关注微信
关注微博


友情链接:生物谷 虚位以待

沪ICP备14043986号-3  |  本站内容争议、广告、业务合作咨询、投稿等请联系:admin@stemcell.xin  
                                                                  Copyright(C)国家干细胞转化资源库&华东干细胞库|技术支持:上海优祺生物医药科技有限公司